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An app called Karabiner fixed the issue for me. https://pqrs.org/osx/karabiner/
I used a MS specific section to fix the Windows/Alt Command/Option key problem, though just reversing the keys via the standard Option/Command modifiers area works fine too.
The Number keypad was fixed by a Logitech specific command:
And now everything that I need works for me. Function keys and volume/mute keys, etc. all work. I never used the programmable keys, but I think with Karabiner and event viewer, you could make any and all of it do whatever you'd like.
Best of luck to all of you. I'm back in.
Regards,
Bill